Understanding the heterogeneous drug response of cancer patients is essential to precision oncology.Pioneering genomic analyses of individual cancer subtypes have begun to identify key determinants of resistance, including up-regulation of multi-drug resistance (MDR) genes and mutational alterations of drug targets.However, these alterations are su
Abstract Background Complement component 3 (C3) glomerulopathy, which includes dense deposit disease (DDD) and C3 glomerulonephritis, is caused by dysregulation of the alternative complement pathway.In most cases, C3 glomerulopathy Hubcap manifests pathologically with membranoproliferative glomerulonephritis-like features.An association between C3
Aspects of humour appearing in society, religion, literature and speech have been discussed.The article investigated in particular the current tendency to interpret certain passages in Drum Sticks the Bible as evidence of humorous traits.In these cases humour is taken as an interpretative key.A prerequisite to provide a hermeneutical basis for read
We present a parametric analysis of gap variation between the lap brace and through brace of YT welded joints for rolled-steel circular hollow sections on plane steel structures.Our aim is to investigate the collapse behavior of YT-joints under lap brace axial compression.In particular, we focus on e/d0 ratios above 0.25 so bending moments can be t
Summer Outfit The development of quality Indonesian human resources is strongly influenced by the success of early childhood education.Problems in the field of law today require solving strategies from various fields.Early childhood education is a very important field in participating in solving legal problems in Indonesia.This writing provides an